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CARTaGENE is a population based biobank and a large ongoing and long-term health study of men and women in Québec, and a regional cohort member of the Canadian Partnership for Tomorrow Project.〔http://www.partnershipfortomorrow.ca/〕 The project's core mandate is to identify the genetic and environmental causes of common chronic diseases affecting the Québec population. The overall objective from a public health perspective is to develop personalized medicine and public policy initiatives targeting high-risk groups.〔 The CARTaGENE Biobank is under the scientific direction of Anne-Monique Nuyt, M.D., and Sébastien Jacquemont, M.D., of the Sainte-Justine Children’s Hospital University Health Center. Based in Montréal Québec, Canada, CARTaGENE is operated under the infrastructure of the Sainte-Justine Children’s Hospital University Health Center and has seen funding from Genome Canada, the Canadian Foundation for Innovation and Génome Québec〔http://www.genomequebec.com/〕 and the Canadian Partnership Against Cancer (CPAC) since 2007 among other sources.〔(【引用サイトリンク】url=http://www.cartagene.qc.ca/en )〕 The program was initially founded by Professor Emeritus Claude Laberge, and developed through two phases of participant recruitment under the direction of Professor Philip Awadalla. == Design == The CARTaGENE Biobank is an infrastructure set up to recruiting men and women aged 40–69 years old from Québec representing an age range most at risk for developing chronic diseases, including cardiovascular disease, metabolic disorders like diabetes mellitus and cancer among others.〔 Taking place between August 2009 and October 2010, 20 007 participants were enrolled in its first phase of recruitment (Phase A) and between December 2012 and February 2015 a new wave of recruitment (Phase B) has enrolled an additional 20 000 participants.〔 The participants were randomly selected and tracked based on their files in the governmental health administrative databases (RAMQ-Régie de l’Assurance Maladie du Québec).〔 Participants were also selected to be representative of 1% of the metropolitan areas of Québec, specifically Montreal, Québec city, Sherbrooke and the Saguenay.〔 Because of administrative linkage between the RAMQ and the CHU Sainte-Justine, participants can be passively followed for the next 50 years making it one of the longest and largest ongoing population studies in the world.〔 Information packages about the project were first sent by mail and potential participants were contacted by telephone to enroll and schedule visits to one of the clinical assessment sites.〔 Moreover, CARTaGENE is part of a Canada-wide cohort collecting samples across the country whose methods were applied in the design of the five cohorts within the Canadian Partnership for Tomorrow Project〔http://www.partnershipfortomorrow.ca〕 (CPTP).〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「CARTaGENE biobank」の詳細全文を読む スポンサード リンク
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